BellBrook Labs官网:https://www.bellbrooklabs.com/
BellBrook成立于2002年,致力于蛋白质靶标的高通量筛选工具,助力全球制药和生物技术公司、CRO 和学术实验室加速药物发现。旗舰Transcreener 高通量筛选 (HTS) 平台产品,可以提供的直接检测有:ADP2,AMP2/GMP2,GDP,UDP2等检测。这些检测组合可覆盖上千种靶酶,包括所有的激酶、 ATP酶和GTP酶,已被世界各地的制药和生物技术筛选实验室迅速验证和采用。
您能用Transcreener做什么?
筛选小分子抑制剂
确定酶的活性
分析抑制剂的效力/确定IC50值
测量先导分子与目标的停留时间/脱落率/解离度
抑制剂的选择性分析
作用机制研究
Transcreener的优势是什么?
通用 - 几乎可用于任何激酶
直接检测核苷酸酶的产物,消除了增加检测干扰的复杂耦合步骤
Transcreener灵敏度高,数据准确,底物转化率低于10%的情况下产生大于0.7的Z'值
通过对整个激酶家族使用同一套试剂,为您节省时间和开发成本
您可以选择FP、FI和TR-FRET读数,并在主要的多模式读数器上获得认证性能
试剂和信号的超长稳定性(过夜),确保大型自动筛选数据的可靠与稳健
安全、无放射性的检测方法
实时测量酶的活性,允许在HTS格式中确定停留时间。
作为BellBrook在中国的独家代理,艾美捷科技有限公司将为中国客户提供全面的BellBrook产品。下图为BellBrook公司授权艾美捷科技有限公司(AmyJet Scientific Inc.)作为BellBrook在中国区域的独家代理授权书。
BellBrook特色产品推荐:
货号 | 产品名称 | 目录价 | 品牌 |
3009-1K | Transcreener? GDP FP Assay | 7126 | BellBrook Labs |
3009-10K | Transcreener? GDP FP Assay | 34986 | BellBrook Labs |
3009-100K | Transcreener? GDP FP Assay | 询价 | BellBrook Labs |
3010-1K | Transcreener? ADP2 FP Assay | 9226 | BellBrook Labs |
3010-10K | Transcreener? ADP2 FP Assay | 53046 | BellBrook Labs |
3010-100K | Transcreener? ADP2 FP Assay | 询价 | BellBrook Labs |
3011-1K | Transcreener? ADP2 TR-FRET Red Assay | 10066 | BellBrook Labs |
3011-10K | Transcreener? ADP2 TR-FRET Red Assay | 57526 | BellBrook Labs |
3011-100K | Transcreener? ADP2 TR-FRET Red Assay | 询价 | BellBrook Labs |
3013-A | Transcreener? ADP2 FI Assay | 4606 | BellBrook Labs |
3013-1K | Transcreener? ADP2 FI Assay | 9646 | BellBrook Labs |
3013-10K | Transcreener? ADP2 FI Assay | 55846 | BellBrook Labs |
3013-100K | Transcreener? ADP2 FI Assay | 询价 | BellBrook Labs |
3014-A | Transcreener? GDP FI Assay | 4606 | BellBrook Labs |
3014-1K | Transcreener? GDP FI Assay | 7406 | BellBrook Labs |
3014-10K | Transcreener? GDP FI Assay | 36246 | BellBrook Labs |
3014-100K | Transcreener? GDP FI Assay | 询价 | BellBrook Labs |
3015-1K | Transcreener? AMP2/GMP2 FP Assay | 9226 | BellBrook Labs |
3015-10K | Transcreener? AMP2/GMP2 FP Assay | 53046 | BellBrook Labs |
3015-100K | Transcreener? AMP2/GMP2 FP Assay | 询价 | BellBrook Labs |
3017-1K | Transcreener? EPIGEN Methyltransferase Assay | 13650 | BellBrook Labs |
3017-10K | Transcreener? EPIGEN Methyltransferase Assay | 81900 | BellBrook Labs |
3017-100K | Transcreener? EPIGEN Methyltransferase Assay | 询价 | BellBrook Labs |
3018-1K | Transcreener? UDP2 FP Far Red Assay | 9226 | BellBrook Labs |
3018-10K | Transcreener? UDP2 FP Far Red Assay | 53046 | BellBrook Labs |
3018-100K | Transcreener? UDP2 FP Far Red Assay | 询价 | BellBrook Labs |
3019-A | Transcreener? UDP2 FI Assay | 4606 | BellBrook Labs |
3019-1K | Transcreener? UDP2 FI Assay | 9646 | BellBrook Labs |
3019-10K | Transcreener? UDP2 FI Assay | 55846 | BellBrook Labs |
3019-100K | Transcreener? UDP2 FI Assay | 询价 | BellBrook Labs |
3020-1K | Transcreener? AMP2/GMP2 TR-FRET Assay | 10066 | BellBrook Labs |
3020-10K | Transcreener? AMP2/GMP2 TR-FRET Assay | 57526 | BellBrook Labs |
3020-100K | Transcreener? AMP2/GMP2 TR-FRET Assay | 询价 | BellBrook Labs |
3021-1K | Transcreener? GDP TR-FRET Assay | 8106 | BellBrook Labs |
3021-10K | Transcreener? GDP TR-FRET Assay | 37226 | BellBrook Labs |
3021-100K | Transcreener? GDP TR-FRET Assay | 询价 | BellBrook Labs |
3022-1K | Transcreener? UDP2 TR-FRET Assay | 10066 | BellBrook Labs |
3022-10K | Transcreener? UDP2 TR-FRET Assay | 57526 | BellBrook Labs |
3022-100K | Transcreener? UDP2 TR-FRET Assay | 询价 | BellBrook Labs |
3023-B | AptaFluor? SAH Methyltransferase Assay | 5250 | BellBrook Labs |
3023-1K | AptaFluor? SAH Methyltransferase Assay | 16450 | BellBrook Labs |
3023-10K | AptaFluor? SAH Methyltransferase Assay | 97986 | BellBrook Labs |
3023-100K | AptaFluor? SAH Methyltransferase Assay | 询价 | BellBrook Labs |
3024-1K | Transcreener? cGAMP cGAS FP Assay | 11172 | BellBrook Labs |
3024-1K-B | Transcreener? cGAMP cGAS FP Assay Bundle | 21675 | BellBrook Labs |
3024-10K | Transcreener? cGAMP cGAS FP Assay | 64610 | BellBrook Labs |
3024-10K-B | Transcreener? cGAMP cGAS FP Assay Bundle | 113390 | BellBrook Labs |
3024-100K | Transcreener? cGAMP cGAS FP Assay | 询价 | BellBrook Labs |
3025-1K | Transcreener? cGAMP cGAS TR-FRET Assay | 12250 | BellBrook Labs |
3025-1K-B | Transcreener? cGAMP cGAS TR-FRET Assay Bundle | 22865 | BellBrook Labs |
3025-10K | Transcreener? cGAMP cGAS TR-FRET Assay | 69846 | BellBrook Labs |
3025-10K-B | Transcreener? cGAMP cGAS TR-FRET Assay Bundle | 118915 | BellBrook Labs |
3025-100K | Transcreener? cGAMP cGAS TR-FRET Assay | 询价 | BellBrook Labs |
3026-1K | Transcreener? CD73 FP Assay | 13930 | BellBrook Labs |
3026-10K | Transcreener? CD73 FP Assay | 79786 | BellBrook Labs |
3026-100K | Transcreener? CD73 FP Assay | 询价 | BellBrook Labs |
3027-1K | Transcreener? OAS FP Assay | 13930 | BellBrook Labs |
3027-10K | Transcreener? OAS FP Assay | 79786 | BellBrook Labs |
3027-100K | Transcreener? OAS FP Assay | 询价 | BellBrook Labs |
2227 | Recombinant cGAS Enzyme, Active, Human, Full-Length (10ug) | 5586 | BellBrook Labs |
2228 | Recombinant cGAS Enzyme, Active, Human, Full-Length (100ug) | 19572 | BellBrook Labs |
2239 | Recombinant cGAS Enzyme, Active, Mouse, Full-Length (10ug) | 5586 | BellBrook Labs |
2249 | Recombinant OAS1 Enzyme, Active, Human, Full-Length (10ug) | 3990 | BellBrook Labs |
2251 | Recombinant DDX3 Enzyme, Active, Human (10ug) | 5586 | BellBrook Labs |
2252 | Recombinant DDX3 Enzyme, Active, Human (100ug) | 19586 | BellBrook Labs |
2253 | Recombinant DDX3 Enzyme, Active, Human (1,000ug) | 68586 | BellBrook Labs |
*以上产品均为科研用途,不得用于医疗.
BellBrook Labs试剂盒广泛的设备兼容性:
设备厂家 | 设备型号 | FP Assays | FI Assays | TR-FRET Assays |
ADP2, AMP2/GMP2, GDP, UDP, EPIGEN SAH, cGAMP, ADO | ADP2, GDP, UDP | ADP2, AMP2/GMP2, GDP, UDP, AptaFluor SAH, cGAMP | ||
TriStar?S LB 942 | 评估中... | |||
Mithras? LB 943 | 评估中... | |||
Cytation? 5 | 已验证! | 已验证! | 已验证! | |
Cytation? 3 | 已验证! | 已验证! | 已验证! | |
Cytation? 1 | 已验证! | 已验证! | 已验证! | |
Synergy? H1 | 已验证! | 已验证! | 已验证! | |
Synergy? 2/H4/4 | 已验证! | 已验证! | 已验证! | |
Synergy? HTX | 不兼容 | 已验证! | 不兼容 | |
Synergy? Neo 2 | 已验证! | 已验证! | 已验证! | |
POLARstar? Omega | 已验证! | 已验证! | 已验证! | |
FLUOstar? Omega | 不兼容 | 已验证! | 已验证! | |
PHERAstar? FSX | 已验证! | 已验证! | 已验证! | |
PHERAstar? Plus/FS | 已验证! | 已验证! | 已验证! | |
CLARIOstar? /Plus | 已验证! | 已验证! | 已验证! | |
VANTAstar? | 已验证! | 已验证! | 已验证! | |
Sense | 评估中... | 已验证! | 评估中... | |
Analyst? GT/HT | 已验证! | 已验证! | 已验证! | |
Gemini? XPS/EM | 不兼容 | 已验证! | 不兼容 | |
SpectraMax? M2/M2e | 不兼容 | 已验证! | 不兼容 | |
SpectraMax? M5/M5e/FlexStation? 3 | 不兼容 | 已验证! | 已验证! | |
SpectraMax? Paradigm | 已验证! | 联系我们 | 联系我们 | |
SpectraMax? iD3/iD5 | 评估中... | 已验证! | 已验证! | |
EnVision?/EnVision? Xcite | 已验证! | 已验证! | 已验证! | |
Infinite? M1000/M1000Pro/Safire2? | 已验证! | 已验证! | 已验证! | |
Infinite? M200 | 不兼容 | 已验证! | 不兼容 | |
Infinite? F500 | 已验证! | 已验证! | 已验证! | |
Infinite? F200/Ultraevolution | 联系我们 | 已验证! | 联系我们 | |
Spark? 10M | 已验证! | 已验证! | 已验证! |
BellBrook Labs 旗舰产品货号与说明书下载(点击超链接) | ||||
检测方式 | FP Assays | FI Assays | TR-FRET Assays | |
荧光偏振 | 荧光法 | 时间分辨 | ||
设备认证标志 | ||||
检测指标 | Transcreener? ADP2 Assay | |||
Transcreener? AMP2/GMP2 Assay | —— | |||
Transcreener? ADO CD73 Assay | —— | —— | ||
Transcreener? 2-5A OAS Assay | —— | —— | ||
Transcreener? cGAMP cGAS Assay | —— | |||
Transcreener? GDP Assay | ||||
Transcreener? UDP2 Assay | ||||
Transcreener? EPIGEN Methyltransferase Assay | —— | —— | ||
AptaFluor? SAH Methyltransferase Assay | —— | —— | ||
配件耗材 | Black Assay Plates | 2233 (3*96-well = 200+ assays) | —— | |
White Assay Plates | —— | 2234 (3*96-well = 200+ assays) | ||
规格说明 | -A:96孔板,50ul反应体系. |
更多产品及产品的详细说明、价格、货期等信息,请联系BellBrook Labs 独家代理。
Transcreener cGAMP cGAS检测法通过测定生成的cGAMP来测定cGAS酶的活性。cGAS分析可用于荧光偏振(FP)和时间分辨-荧光共振能量转移(TR-FRET)两种方式进行检测~
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